Author(s)
Dr. Bhawesh Kumar Yadav, Dr. Nabin Kumar Yadav, Dr. Surendra Prasad Saha, Dr. Khudabakhash Yaqoob, Dr. Bibha Yadav
- Manuscript ID: 120575
- Volume 2, Issue 5, May 2026
- Pages: 485–493
Subject Area: Neuroscience
DOI: https://doi.org/10.5281/zenodo.20367181Abstract
Computed Tomography Angiography (CTA) is increasingly used as a non-invasive, rapid diagnostic modality for detecting cerebral aneurysms and arteriovenous malformations (AVMs), especially in resource-limited settings. This study analyzed simulated findings from 200 patients based on published literature, incorporating clinical scenarios from BPKIHS (Nepal), Jalal-Abad State University (Kyrgyzstan), and Ayushman Hospital (India). All patients underwent CTA followed by Digital Subtraction Angiography (DSA) as the reference standard. CTA demonstrated a sensitivity of 85.5% and specificity of 94.4% for aneurysm detection, with performance improving significantly for aneurysms larger than 5 mm. For AVMs, CTA showed 90% sensitivity and 96.7% specificity. While CTA was less sensitive for aneurysms smaller than 3 mm, it reliably detected larger aneurysms and most AVMs, particularly those in eloquent regions. These results support CTA as a valuable first-line imaging tool for cerebrovascular evaluation, offering practical advantages in triaging patients and guiding intervention decisions in diverse clinical environments.
Background:
CT angiography (CTA) is a rapid, noninvasive alternative to digital subtraction angiography (DSA) for cerebrovascular imaging. It is used to evaluate patients with suspected aneurysms or arteriovenous malformations (AVMs).