FORMULATION AND EVALUATION OF POLYHERBAL GEL FROM PSIDIUM GUAJAVA EXTRACT FOR MOUTH ULCER

Abstract

Herbal medicines is still the mainstay of about 75-80% of the world’s population, mainly in developing countries, for primary health care because of better cultural acceptability, better compatibility with human body and lesser side effects. Herbal medicines consist of plant or its part to treat injuries, disease or illnesses and are used to prevent and treat diseases and ailments or to promote health and healing.
It is a drug or preparation made from a plant or plants and used for any to such purpose. Herbal medicines are the oldest form of health care known to mankind. A gel is a soft, solid or solid-like material which consists of at least two components, one of them being a liquid, present in substantial quantity. There are number of synthetic gels in the market as compared to herbal or natural gel, but synthetic gels has some harmful effects on skin like irritation and dryness of skin.
Now a day’s peoples are more aware about side effects and each and every ingredient using formulation of gel or any other formulation. Hencedue to this reason there is increasing demand for natural ingredient containing formulation.
The aim of this project was to formulate and evaluate herbal mouth ulcer gel. Therefore, developed formulations have potential to treat mouth ulcers. However, further clinical studies are required to establish clinical efficacy of prepared herbal gels.
Herbal gel was prepared by using different concentration of powdered guava leaves and Carbopol 934, Propylene glycol as a gel base.
From the experimental evidence of investor studies it was observed that powdered guava leaves contain flavonoids so it showed significant antioxidant effect. Developed herbal formulation was stable, safe and effective over to synthetic formulations for the treatment of mouth ulcer.

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